1-Hydroxybenzotriazole monohydrate (HOBT)

1-Hydroxybenzotriazole monohydrate (HOBT)

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HOBt can be used to produce activated esters such as N-hydroxysuccinimide ester. These esters are insoluble and react with amines at ambient temperature to give amides [1]. HOBt is also used for the synthesis of amides from carboxylic acidsaside from amino acids.
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